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ASTS 17th Annual State of the Art Winter Symposium
January 26–29, 2017
Loews Miami Beach Hotel

Friday, January 27, 2017

12:00–12:15 p.m. Welcome & CME/MOC Overview
Daniela P. Ladner
Northwestern Memorial Hospital
Matthew H. Levine, MD, PhD
University of Pennsylvania
12:15–12:30 p.m. The Road to Perdition: How Did We Get Here?
Carlos O. Esquivel, MD, PhD
Stanford University
12:30–12:50 p.m. National Treasure: Have We Achieved Pare to Optimization in Transplantation?
Michael M. Abecassis, MD, MBA
Northwestern University
12:50–1:10 p.m. No Country for Old Men
Anji E. Wall, MD, PhD
Stanford University
1:10–1:30 p.m. Around the World in 80 Days: Solutions from Other Countries
Paul Greig, MD, FRSC
University of Toronto
1:30–2:00 p.m. Hume Lecture
A. Benedict Cosimi, MD
Massachusetts General Hospital
2:15–3:45 p.m. Oral Abstract Session
Moderators:
Ginny L. Bumgardner, MD, PhD
Alp Sener, MD, PhD

MELD as a Metric for Survival Benefit of Liver Transplantation
Xun Luo, MD, MPH
Johns Hopkins University

Refusal to Accept CDC-Increased Infectious Risk Kidney Offers Associated
with Poor Waitlist Survival

Mary Grace Bowring, MPH
Johns Hopkins University

Progress and Hurdles in Preclinical Model of Tolerance Induction Using
Combined Liver and Bone Marrow Transplant (CLBMT)

Samuel Gavzy
Columbia Center for Translational Immunology, Columbia University

Live Donor Characteristics Predict Recipient and Graft Survival In Liver
Transplantation

Joshua Shaw, MD
University of Toronto

Pre-Transplant Circulating TNFR2+ Regulatory T Cells Predict Acute
Rejection Within the First 6 Months After Kidney Transplantation

Minh-Tri Nguyen, MD
Columbia University

Increased Involvement of Advanced Practice Providers Improves Care
Coordination and Outcomes Among Liver Transplant Recipients

Jennifer Sharp, MS
University of Michigan

PPAR-γ Agonist Attenuates Hepatic Ischemia-Reperfusion Injury in Mice
by Inducing M2 Kupffer Cell Polarization

Ivan Linares-Cervantes
Toronto General Hospital

Synthetic Liver Function is Preserved in Transgenic Porcine Livers
Perfused with Human Blood

Jessica Powell
University of Maryland School of Medicine

Generation of Insulin Producing Cells from Human Intestinal Tissue
Priya Dedhia
University of Michigan
DEBATES
Moderators:
William C. Chapman, MD
Karim J. Halazun, MD
3:45–4:15 p.m. Touching the Void: MELD- Sickest First vs. Greatest Benefit
Pro: Ryutaro Hirose, MD
Con: Avi Shaked, MD, PhD
4:15–4:45 p.m.
Game of Thrones: OPO vs. Transplant Centers: How to Align the Objectives of these Organizations for the Benefit of the Patient
Jay Campbell, JD
Nikole Neidlinger, MD
Timothy L. Pruett, MD
5:00–7:30 p.m.
Opening Poster & Exhibit Hall Reception

Saturday, January 28, 2017

8:00–8:15 a.m. Dead Man Walking: Landscape of DCD
Colleen L. Jay, MD, MS
University of Texas Health Science Center
8:15–8:35 a.m.
Money Talks: DCD Cost Benefit Analysis
MB Majella Doyle, MD, MBA
Washington University School of Medicine, St. Louis
8:35–8:55 a.m.
Pimp My Ride: DCD Utilization in the Setting of Machine Profusion
Darius Mirza
8:55–9:15 a.m.
Awards Presentation
9:15–10:25 a.m.
Oral Abstract Session II
Moderators:
Peter G. Stock, MD, PhD
Matthew H. Levine, MD, PhD

No Country for Old Livers? Examining and Optimizing the Use of Elderly
Liver Grafts

Karim J. Halazun, MD
Weill Cornell Medical College

OPO Strategies to Prevent Unintended Use of Kidneys Exported For High PRA Patients
Anil Paramesh, MD, FACS
Tulane Transplant Institute

Inhibition of CoREST Reverses HDAC2-Mediated Protection from Renal
Ischemia

David Aufhauser, MD
University of Pennsylvania

Donor-derived Cell-free DNA Predicts Biopsy-proven Acute Cellular
Rejection in Pediatric Kidney Transplant Recipients

Daniel Stoltz, BS
Stanford University

Heart Donor Cocaine Use Does Not Increase the Risk Of Graft
Atherosclerosis

A. Michael Borkon, MD
Mid America Heart Institute of St. Luke’s Hospital

Survival Benefit with Kidney Transplants from HLA-Incompatible Live
Donors

Babak J. Orandi, MD, MSc, PhD
Johns Hopkins University

Individualizing Liver Transplant Immunosuppression Using Phenotypic
Personalized Medicine Platform

Ali Zarrinpar, MD, PhD
The Dumont-UCLA Transplant Center
10:45–10:55 a.m. Analyze That: Ongoing Policy Efforts for Deceased Donor Intervention
Sandy S. Feng, MD, PhD
University of California, San Francisco
10:55–11:05 a.m.
ORGANIZE
Greg Segal
ORGANIZE Co-Founder
11:05–11:15 a.m.
Indecent Proposal? Financial Incentives
John C. Magee, MD
University of Michigan Medical Center
11:15–11:25 a.m.
The Breakup: Splitting Today and Splitting in the Future
Charles M. Miller, MD
Cleveland Clinic
11:25 a.m.–12:00 p.m.
Win Win: Panel Discussion
Dixon B. Kaufman, MD, PhD
George E. Loss, MD
Darius Mirza
Lloyd E. Ratner, MD, MPH
12:00–12:30 p.m.
Presidential Address
Timothy L. Pruett, MD
University of Minnesota
1:00–3:15 p.m. Education Workshop
7:00–10:00 p.m.
Winter Symposium Dinner & Dancing
Americana Lawn

Sunday, January 29, 2017

8:00–9:00 a.m. Sex, Lies and Videotape: Video Abstract Session
Moderator:
James J. Pomposelli, MD, PhD
9:00–10:00 a.m.
Mini-Oral Abstract Session
Moderators:
Kenneth D. Chavin, MD, PhD
Derek E. Moore, MD, MPH

Effects of Systems Improvement Agreements on Waitlist Patient
Outcomes

Lauren Nicholas, PhD
Johns Hopkins School of Public Health

Results of High Risk Donation-after-Circulatory Death (DCD) Donor Liver
Transplants

Narendra Battula, FRCS
Ochsner Clinical Foundation

Liver Graft Modification Using Warm Ex Vivo Perfusion - It Isn’t Only
About Rescuing Marginal Grafts

Nicholas Goldaracena, MD
Toronto General Hospital

Age is an Effect Modifier of Racial Disparities in Heart Transplant Survival
Hasina Maredia
Johns Hopkins University

Survival Outcomes from DCD Renal Transplant Are Comparable to DBD
Renal Transplant from Kidneys Procured from Donors More Than 50
Years of Age. A UNOS/OPTN Analysis

Hemant Sherma
London Health Science Centre

Racial Differences in Liver Cirrhosis-Related Mortality among Patients
with a Low Model for End-Stage Liver Disease Sodium Score (MELDNa) <15

Kofi Atiemo, MD
Northwestern University

Progress Towards Liver Xenotransplantation Serving as A Bridge to
Allotransplantation

Jigesh Shah, DO
Massachusetts General Hospital/Harvard Medical School

Highly Sensitized Patients Undergoing Simultaneous Liver Kidney
Transplantation (SLKT): Should We Desensitize?

Justin Steggerda
Cedars Sinai Medical Center
10:15–10:25 a.m.
The Wall: Barriers to Increased Utilization
Jesse Schold, PhD, M.Stat, M.Ed
Cleveland Clinic
10:25–11:35 a.m. Soap Box Session: Fix the System
Changing Metrics for Increasing Utilization
11:35 a.m.–12:00 p.m.
Say Anything: Panel Discussion